Version 5.4
Mus musculus Protein: Uchl4
Summary
InnateDB Protein IDBP-176168.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uchl4
Protein Name ubiquitin carboxyl-terminal esterase L4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000045208
InnateDB Gene IDBG-176166 (Uchl4)
Protein Structure
UniProt Annotation
Function Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in various tissues at low level.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1890440
InterPro IPR001578 Peptidase C12, ubiquitin carboxyl-terminal hydrolase
PFAM PF01088
PRINTS PR00707
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58321
PhosphoSite PhosphoSite-P58321
TrEMBL B2RTM4
UniProt Splice Variant
Entrez Gene 93841
UniGene Mm.390180
RefSeq NP_291085
MGI ID
MGI Symbol Uchl4
OMIM
CCDS CCDS23278
HPRD
IMGT
EMBL AB035420 BC139440 BC139441 CH466522
GenPept AAI39441 AAI39442 BAB47122 EDL26059

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca