Version 5.4
Mus musculus Protein: Nup54
Summary
InnateDB Protein IDBP-180078.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nup54
Protein Name nucleoporin 54
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000046540
InnateDB Gene IDBG-180076 (Nup54)
Protein Structure
UniProt Annotation
Function Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. {ECO:0000250}.
Subcellular Localization Nucleus, nuclear pore complex {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Nucleoplasmic side {ECO:0000250}. Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005487 nucleocytoplasmic transporter activity
GO:0005515 protein binding
Biological Process
GO:0006605 protein targeting
GO:0006913 nucleocytoplasmic transport
GO:0051028 mRNA transport
Cellular Component
GO:0005643 nuclear pore
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:1920460
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BTS4
PhosphoSite PhosphoSite-Q8BTS4
TrEMBL
UniProt Splice Variant
Entrez Gene 269113
UniGene Mm.427807
RefSeq NP_899248
MGI ID
MGI Symbol Nup54
OMIM
CCDS CCDS19430
HPRD
IMGT
EMBL AK087827 AK088855 AK133841 AK162037 BC068114
GenPept AAH68114 BAC40018 BAC40615 BAE21878 BAE36693

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca