Version 5.4
| Mus musculus Protein: Gm5077 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-187206.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Gm5077 | ||||||||
| Protein Name | predicted gene 5077 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000066999 | ||||||||
| InnateDB Gene | IDBG-255878 (Gm5077) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Specifically expressed in male reproductive tissues. {ECO:0000269PubMed:12513694}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:3644269 | ||||||||
| InterPro |
IPR000436
Sushi/SCR/CCP IPR000859 CUB domain IPR001254 Peptidase S1 IPR001314 Peptidase S1A, chymotrypsin-type IPR001881 EGF-like calcium-binding domain IPR009003 Trypsin-like cysteine/serine peptidase domain |
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| PFAM |
PF00084
PF00431 PF00089 PF07645 |
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| PRINTS |
PR00722
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| PIRSF | |||||||||
| SMART |
SM00032
SM00042 SM00020 SM00179 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8CFG8 | ||||||||
| PhosphoSite | PhosphoSite-Q8CFG8 | ||||||||
| TrEMBL | W4VSN5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 317677 | ||||||||
| UniGene | Mm.483270 | ||||||||
| RefSeq | NP_776289 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | C1s2 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS20522 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC115911 AF459020 CH466523 | ||||||||
| GenPept | AAO15559 EDK99743 EDK99744 | ||||||||