Version 5.4
Mus musculus Protein: Tas2r103
Summary
InnateDB Protein IDBP-193864.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tas2r103
Protein Name taste receptor, type 2, member 103
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000032317
InnateDB Gene IDBG-193862 (Tas2r103)
Protein Structure
UniProt Annotation
Function Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. Expressed in 15% taste bud cells in circumvallate and foliate papillae but only in 2% in fungiform papillae.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1890257
InterPro IPR007960 Mammalian taste receptor
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF05296
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JKA3
PhosphoSite PhosphoSite-AAF64509
TrEMBL
UniProt Splice Variant
Entrez Gene 667992
UniGene Mm.479865
RefSeq NP_444441
MGI ID
MGI Symbol Tas2r103
OMIM
CCDS CCDS51933
HPRD
IMGT
EMBL AC152822 AF247732 BK001091
GenPept AAF64509 DAA01230

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca