Version 5.4
Mus musculus Protein: Il31
Summary
InnateDB Protein IDBP-199638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il31
Protein Name interleukin 31
Synonyms 1700013B14Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000031389
InnateDB Gene IDBG-199636 (Il31)
Protein Structure
UniProt Annotation
Function Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. {ECO:0000269PubMed:15184896}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
Biological Process
GO:0002376 immune system process
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:1923649
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6EAL8
PhosphoSite PhosphoSite-
TrEMBL Q9DAD2
UniProt Splice Variant
Entrez Gene 76399
UniGene Mm.75049
RefSeq NP_083870
MGI ID
MGI Symbol Il31
OMIM
CCDS CCDS51645
HPRD
IMGT
EMBL AK005939 AY509149 BC117082 BC117084
GenPept AAI17083 AAI17085 AAS82846 BAB24326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca