InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nlrp1b

Summary

InnateDB Protein

IDBP-264373.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Nlrp1b

Protein Name

NLR family, pyrin domain containing 1B

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104155

InnateDB Gene

IDBG-195961 (Nlrp1b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0030163	protein catabolic process
GO:0032610	interleukin-1 alpha production
GO:0032611	interleukin-1 beta production
GO:0042981	regulation of apoptotic process
GO:0070269	pyroptosis

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

MGI:3582959

InterPro

IPR001315 CARD domain
IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00619

PRINTS

PIRSF

SMART

SM00114
SM00368

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite