Version 5.4
Mus musculus Protein: Psme2b-ps
Summary
InnateDB Protein IDBP-272167.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Psme2b-ps
Protein Name protease (prosome, macropain) 28 subunit beta B, pseudogene
Synonyms AA589371; AI788882; PA28b;
Species Mus musculus
Ensembl Protein ENSMUSP00000100564
InnateDB Gene IDBG-272165 (Psme2b-ps)
Protein Structure
UniProt Annotation
Function Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0008537 proteasome activator complex
Protein Structure and Domains
PDB ID MGI:1341073
InterPro IPR003185 Proteasome activator pa28, N-terminal domain
IPR003186 Proteasome activator pa28, C-terminal domain
IPR009077 Proteasome activator pa28
PFAM PF02251
PF02252
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P97372
PhosphoSite PhosphoSite-P97372
TrEMBL Q99LN3
UniProt Splice Variant
Entrez Gene 621823
UniGene
RefSeq NP_001268401
MGI ID
MGI Symbol Psme2b
OMIM
CCDS
HPRD
IMGT
EMBL AB007138 AB053120 AF060195 AF115502 AK012344 AK088654 AK143556 BC002301 BC005680 BC057859 CH466535 D87910 U60329
GenPept AAC53296 AAC83999 AAD38121 AAH02301 AAH05680 AAH57859 BAA22040 BAA28837 BAB28175 BAB47405 BAC40481 BAE25433 EDL36279

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca