Homo sapiens Protein: AQP10 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-474524.4 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | AQP10 | ||||||||
Protein Name | aquaporin 10 | ||||||||
Synonyms | |||||||||
Species | Homo sapiens | ||||||||
Ensembl Protein | ENSP00000420341 | ||||||||
InnateDB Gene | IDBG-102927 (AQP10) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. {ECO:0000269PubMed:11573934, ECO:0000269PubMed:12084581}. | ||||||||
Subcellular Localization | Membrane; Multi-pass membrane protein. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | |||||||||
InterPro |
IPR000425
Major intrinsic protein IPR023271 Aquaporin-like IPR023275 Aquaporin 3 IPR026252 Aquaporin 10 |
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PFAM |
PF00230
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PRINTS |
PR00783
PR02015 PR02022 |
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PIRSF | |||||||||
SMART | |||||||||
TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | Q96PS8 | ||||||||
PhosphoSite | PhosphoSite- | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 89872 | ||||||||
UniGene | Hs.259048 | ||||||||
RefSeq | |||||||||
HUGO | HGNC:16029 | ||||||||
OMIM | 606578 | ||||||||
CCDS | |||||||||
HPRD | 07361 | ||||||||
IMGT | |||||||||
EMBL | AB066105 AF159174 AL354980 BC069607 BC074896 BC074897 | ||||||||
GenPept | AAH69607 AAH74896 AAH74897 AAL25998 BAB91223 CAH70482 CAH70483 | ||||||||