InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SPEF1

Summary

InnateDB Protein

IDBP-48133.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPEF1

Protein Name

sperm flagellar 1

Synonyms

C20orf28; CLAMP; SPEF1A;

Species

Homo sapiens

Ensembl Protein

ENSP00000369080

InnateDB Gene

IDBG-48129 (SPEF1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Note=Present in the tails of developing and epididymal sperm, internal to the fibrous sheath and around the outer dense fibers of the sperm flagellum. Also found at the apical tip of cilia (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005930	axoneme
GO:0031514	motile cilium

Protein Structure and Domains

PDB ID

InterPro

IPR001715 Calponin homology domain
IPR010441 Protein of unknown function DUF1042
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM

PF00307
PF06294
PF11971

PRINTS

PIRSF

SMART

SM00033

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y4P9