InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IL29

Summary

InnateDB Protein

IDBP-50121.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IL29

Protein Name

interleukin 29 (interferon, lambda 1)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000329991

InnateDB Gene

IDBG-50119 (IL29)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005125	cytokine activity
GO:0032003	interleukin-28 receptor binding

Biological Process

GO:0002829	negative regulation of type 2 immune response
GO:0007259	JAK-STAT cascade
GO:0008285	negative regulation of cell proliferation
GO:0032696	negative regulation of interleukin-13 production
GO:0032714	negative regulation of interleukin-5 production
GO:0032729	positive regulation of interferon-gamma production
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
GO:0043381	negative regulation of memory T cell differentiation
GO:0045087	innate immune response (InnateDB)
GO:0045345	positive regulation of MHC class I biosynthetic process
GO:0045581	negative regulation of T cell differentiation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046427	positive regulation of JAK-STAT cascade
GO:0050778	positive regulation of immune response
GO:0051607	defense response to virus