InnateDB Protein
|
IDBP-54198.5
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
SNX4
|
Protein Name
|
sorting nexin 4
|
Synonyms
|
ATG24B;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000251775
|
InnateDB Gene
|
IDBG-54196 (SNX4)
|
Protein Structure
|
|
Function |
May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. {ECO:0000269PubMed:17994011}.
|
Subcellular Localization |
Early endosome membrane {ECO:0000269PubMed:17994011}; Peripheral membrane protein {ECO:0000269PubMed:17994011}; Cytoplasmic side {ECO:0000269PubMed:17994011}. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC).
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
26
[view]
|
Protein-Protein |
26
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001683
Phox homologous domain
|
PFAM |
PF00787
|
PRINTS |
|
PIRSF |
|
SMART |
SM00312
|
TIGRFAMs |
|
Modification |
|
SwissProt |
O95219
|
PhosphoSite |
PhosphoSite-O95219
|
TrEMBL |
Q9H398
|
UniProt Splice Variant |
|
Entrez Gene |
8723
|
UniGene |
Hs.507243
|
RefSeq |
NP_003785
|
HUGO |
HGNC:11175
|
OMIM |
605931
|
CCDS |
CCDS3032
|
HPRD |
09334
|
IMGT |
|
EMBL |
AC080096
AC117487
AF065485
AF130078
AK001835
AK298972
BC018762
CH471052
|
GenPept |
AAC83149
AAG35504
AAH18762
BAG50982
BAG61066
EAW79390
EAW79391
EAW79393
|
|
|