InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BOLA-DIB

Summary

InnateDB Protein

IDBP-680189.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BOLA-DIB

Protein Name

major histocompatibility complex, class II, DY beta

Synonyms

Bola-DIB; DYB;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053987

InnateDB Gene

IDBG-628767 (BOLA-DIB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0015643	toxic substance binding
GO:0031625	ubiquitin protein ligase binding
GO:0042605	peptide antigen binding
GO:0070491	repressing transcription factor binding

Biological Process

GO:0002344	B cell affinity maturation
GO:0002376	immune system process
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0002579	positive regulation of antigen processing and presentation
GO:0002827	positive regulation of T-helper 1 type immune response
GO:0006955	immune response
GO:0019882	antigen processing and presentation
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0046635	positive regulation of alpha-beta T cell activation
GO:0048002	antigen processing and presentation of peptide antigen
GO:0071346	cellular response to interferon-gamma

Cellular Component

GO:0005622	intracellular
GO:0005769	early endosome
GO:0005771	multivesicular body
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042613	MHC class II protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000353 MHC class II, beta chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein

PFAM

PF00969
PF07654

PRINTS

PIRSF

SMART

SM00921
SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q95399

UniProt Splice Variant

Entrez Gene

282498

UniGene

Bt.29870

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02054876 U69097

GenPept

AAB09061