InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MCU

Summary

InnateDB Protein

IDBP-681424.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MCU

Protein Name

mitochondrial calcium uniporter

Synonyms

CCDC109A;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005059

InnateDB Gene

IDBG-629975 (MCU)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005262	calcium channel activity
GO:0005515	protein binding
GO:0015292	uniporter activity
GO:0042802	identical protein binding

Biological Process

GO:0006851	mitochondrial calcium ion transport
GO:0019722	calcium-mediated signaling
GO:0032024	positive regulation of insulin secretion
GO:0035786	protein complex oligomerization
GO:0036444	calcium ion import into mitochondrion
GO:0042593	glucose homeostasis
GO:0051561	positive regulation of mitochondrial calcium ion concentration

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0031305	integral component of mitochondrial inner membrane
GO:0034704	calcium channel complex
GO:1990246	uniplex complex