Version 5.4
Bos taurus Protein: VMA21
Summary
InnateDB Protein IDBP-683476.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VMA21
Protein Name Vacuolar ATPase assembly integral membrane protein VMA21
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008268
InnateDB Gene IDBG-631899 (VMA21)
Protein Structure
UniProt Annotation
Function Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. {ECO:0000255HAMAP-Rule:MF_03058}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000255HAMAP-Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255HAMAP-Rule:MF_03058}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000255HAMAP- Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255HAMAP- Rule:MF_03058}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000255HAMAP-Rule:MF_03058}; Multi-pass membrane protein {ECO:0000255HAMAP-Rule:MF_03058}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly
Cellular Component
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030127 COPII vesicle coat
GO:0031410 cytoplasmic vesicle
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Protein Structure and Domains
PDB ID
InterPro IPR019013 Vacuolar ATPase assembly integral membrane protein VMA21-like domain
PFAM PF09446
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2VDK9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 613674
UniGene Bt.56321
RefSeq NP_001075085
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC133287
GenPept AAI33288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca