InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC2A5

Summary

InnateDB Protein

IDBP-685273.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC2A5

Protein Name

Solute carrier family 2, facilitated glucose transporter member 5

Synonyms

GLUT5;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045621

InnateDB Gene

IDBG-633550 (SLC2A5)

Protein Structure

UniProt Annotation

Function

Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter (By similarity). {ECO:0000250}.

Subcellular Localization

Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Membrane; Multi-pass membrane protein. Note=Localized on the apical membrane of the small intestine and the proximal tubule of the kidney. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005353	fructose transmembrane transporter activity
GO:0022857	transmembrane transporter activity
GO:0022891	substrate-specific transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0008643	carbohydrate transport
GO:0015755	fructose transport
GO:0055085	transmembrane transport
GO:0071332	cellular response to fructose stimulus

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003663 Sugar/inositol transporter
IPR005828 General substrate transporter
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain

PFAM

PF00083

PRINTS

PR00171

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P58353