InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BOLA

Summary

InnateDB Protein

IDBP-686826.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BOLA

Protein Name

MHC class I heavy chain isoform 1

Synonyms

D18.5;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000031126

InnateDB Gene

IDBG-635012 (BOLA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042605	peptide antigen binding

Biological Process

GO:0001916	positive regulation of T cell mediated cytotoxicity
GO:0002376	immune system process
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0006955	immune response
GO:0019882	antigen processing and presentation

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042612	MHC class I protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR010579 MHC class I, alpha chain, C-terminal
IPR011162 MHC classes I/II-like antigen recognition protein
IPR013162 CD80-like, immunoglobulin C2-set
IPR027648 MHC class I alpha chain

PFAM

PF00129
PF07654
PF06623
PF08205

PRINTS

PR01638

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q2TBV8

UniProt Splice Variant

Entrez Gene

515712

UniGene

Bt.96949

RefSeq

NP_001033607

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC109586 DAAA02055406 S47737

GenPept

AAB23971 AAI09587