InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TRAF3

Summary

InnateDB Protein

IDBP-687038.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRAF3

Protein Name

TNF receptor-associated factor 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017918

InnateDB Gene

IDBG-635183 (TRAF3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 121 interaction(s) predicted by orthology.

Predicted by orthology
Total	121 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005164	tumor necrosis factor receptor binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019901	protein kinase binding
GO:0031625	ubiquitin protein ligase binding
GO:0031996	thioesterase binding
GO:0046872	metal ion binding

Biological Process

GO:0001817	regulation of cytokine production
GO:0002224	toll-like receptor signaling pathway
GO:0007165	signal transduction
GO:0008063	Toll signaling pathway
GO:0016567	protein ubiquitination
GO:0030162	regulation of proteolysis
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032648	regulation of interferon-beta production
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0042981	regulation of apoptotic process
GO:0045087	innate immune response
GO:0050688	regulation of defense response to virus