Version 5.4
Bos taurus Protein: DMD
Summary
InnateDB Protein IDBP-690299.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DMD
Protein Name dystrophin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010858
InnateDB Gene IDBG-638239 (DMD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0050998 nitric-oxide synthase binding
Biological Process
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002027 regulation of heart rate
GO:0006355 regulation of transcription, DNA-templated
GO:0007517 muscle organ development
GO:0007519 skeletal muscle tissue development
GO:0008065 establishment of blood-nerve barrier
GO:0010468 regulation of gene expression
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0014819 regulation of skeletal muscle contraction
GO:0014904 myotube cell development
GO:0021629 olfactory nerve structural organization
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0034613 cellular protein localization
GO:0043623 cellular protein complex assembly
GO:0045213 neurotransmitter receptor metabolic process
GO:0046716 muscle cell cellular homeostasis
GO:0048747 muscle fiber development
GO:0051647 nucleus localization
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity
GO:0060857 establishment of glial blood-brain barrier
GO:0086001 cardiac muscle cell action potential
GO:1901385 regulation of voltage-gated calcium channel activity
GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation
GO:2000651 positive regulation of sodium ion transmembrane transporter activity
Cellular Component
GO:0005886 plasma membrane
GO:0016010 dystrophin-associated glycoprotein complex
GO:0030018 Z disc
GO:0030055 cell-substrate junction
GO:0042383 sarcolemma
GO:0044306 neuron projection terminus
GO:0045121 membrane raft
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR000433 Zinc finger, ZZ-type
IPR015153 EF-hand domain, type 1
IPR015154 EF-hand domain, type 2
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00569
PF09068
PF09069
PRINTS
PIRSF
SMART SM00291
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A8WFL6
UniProt Splice Variant
Entrez Gene 540755
UniGene Bt.94479
RefSeq NP_001103554
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149235 DAAA02073842 DAAA02073843
GenPept AAI49236

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca