InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AMELX

Summary

InnateDB Protein

IDBP-691142.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AMELX

Protein Name

Amelogenin, X isoform

Synonyms

AMLX;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016034

InnateDB Gene

IDBG-639021 (AMELX)

Protein Structure

UniProt Annotation

Function

Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.

Subcellular Localization

Secreted, extracellular space, extracellular matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0001649	osteoblast differentiation
GO:0001837	epithelial to mesenchymal transition
GO:0002062	chondrocyte differentiation
GO:0007275	multicellular organismal development
GO:0031214	biomineral tissue development
GO:0032967	positive regulation of collagen biosynthetic process

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR004116 Amelogenin

PFAM

PF02948

PRINTS

PR01757

PIRSF

SMART

SM00818

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P02817

PhosphoSite

PhosphoSite-

TrEMBL

B2D1C9

UniProt Splice Variant

Entrez Gene

281620

UniGene

Bt.28016

RefSeq

NP_001014984

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

EU168863 EU569298 EU569299 M63499 M63631

GenPept

AAA30372 AAA30625 ABY48720 ACB30277 ACB30278