InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PVRL2

Summary

InnateDB Protein

IDBP-691429.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PVRL2

Protein Name

poliovirus receptor-related 2

Synonyms

prr2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020344

InnateDB Gene

IDBG-639286 (PVRL2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0050839	cell adhesion molecule binding

Biological Process

GO:0001675	acrosome assembly
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891	positive regulation of immunoglobulin mediated immune response
GO:0007010	cytoskeleton organization
GO:0007156	homophilic cell adhesion
GO:0007286	spermatid development
GO:0007289	spermatid nucleus differentiation
GO:0009566	fertilization
GO:0019064	fusion of virus membrane with host plasma membrane
GO:0030382	sperm mitochondrion organization
GO:0032990	cell part morphogenesis
GO:0033005	positive regulation of mast cell activation
GO:0042271	susceptibility to natural killer cell mediated cytotoxicity
GO:0044406	adhesion of symbiont to host
GO:0044782	cilium organization
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0046814	virion attachment, binding of host cell surface coreceptor
GO:0051654	establishment of mitochondrion localization
GO:0060370	susceptibility to T cell mediated cytotoxicity

Cellular Component

GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005915	zonula adherens
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF07686
PF08205

PRINTS

PIRSF

SMART

SM00406
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite