Version 5.4
Bos taurus Protein: TBL1X
Summary
InnateDB Protein IDBP-691697.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBL1X
Protein Name F-box-like/WD repeat-containing protein TBL1X
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024105
InnateDB Gene IDBG-639526 (TBL1X)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0042393 histone binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006508 proteolysis
GO:0007605 sensory perception of sound
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627 response to estrogen
GO:0045444 fat cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048545 response to steroid hormone
GO:0060070 canonical Wnt signaling pathway
Cellular Component
GO:0005667 transcription factor complex
GO:0005876 spindle microtubule
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR006594 LisH dimerisation motif
IPR013720 LisH dimerisation motif, subgroup
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF08513
PRINTS PR00320
PIRSF
SMART SM00320
SM00667
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7TCI5
UniProt Splice Variant
Entrez Gene 515972
UniGene Bt.27699
RefSeq NP_001138704
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02075574 FJ195366
GenPept ACJ61274

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca