Version 5.4
Bos taurus Protein: TUBG2
Summary
InnateDB Protein IDBP-692574.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUBG2
Protein Name Tubulin gamma-2 chain
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000040455
InnateDB Gene IDBG-640322 (TUBG2)
Protein Structure
UniProt Annotation
Function Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007017 microtubule-based process
GO:0007020 microtubule nucleation
GO:0031122 cytoplasmic microtubule organization
GO:0051258 protein polymerization
Cellular Component
GO:0000242 pericentriolar material
GO:0000930 gamma-tubulin complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005876 spindle microtubule
GO:0005881 cytoplasmic microtubule
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR000217 Tubulin
IPR002452 Alpha tubulin
IPR002453 Beta tubulin
IPR002454 Gamma tubulin
IPR002967 Delta tubulin
IPR003008 Tubulin/FtsZ, GTPase domain
IPR004057 Epsilon tubulin
IPR008280 Tubulin/FtsZ, C-terminal
IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
IPR019605 Misato Segment II tubulin-like domain
PFAM PF00091
PF03953
PF10644
PRINTS PR01161
PR01162
PR01163
PR01164
PR01224
PR01519
PIRSF
SMART SM00864
SM00865
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32KM1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 540216
UniGene Bt.5418
RefSeq NP_001032704
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC110028
GenPept AAI10029

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca