InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: IFIH1

Summary

InnateDB Protein

IDBP-693556.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IFIH1

Protein Name

interferon induced with helicase C domain 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010703

InnateDB Gene

IDBG-641195 (IFIH1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003727	single-stranded RNA binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0016817	hydrolase activity, acting on acid anhydrides
GO:0043021	ribonucleoprotein complex binding

Biological Process

GO:0009615	response to virus
GO:0016925	protein sumoylation
GO:0042981	regulation of apoptotic process
GO:0045087	innate immune response

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR001315 CARD domain
IPR001650 Helicase, C-terminal
IPR006935 Helicase/UvrB domain
IPR011029 Death-like domain
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR021673 C-terminal domain of RIG-I
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00619
PF00271
PF04851
PF00270
PF11648

PRINTS

PIRSF

SMART

SM00114
SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite