Bos taurus Protein: TBC1D1
Summary
InnateDB Protein IDBP-693972.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D1
Protein Name TBC1 domain family member 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018206
InnateDB Gene IDBG-641589 (TBC1D1)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005097 Rab GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
IPR006020 PTB/PI domain
IPR021785 Protein of unknown function DUF3350
PFAM PF00566
PF00640
PF14719
PF11830
PRINTS
PIRSF
SMART SM00164
SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O97790
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282704
UniGene Bt.4932
RefSeq NP_001159996
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02017438 DAAA02017439 DAAA02017440 DAAA02017441 DAAA02017442 DAAA02017443 Y17923
GenPept CAA76943