Version 5.4
| Bos taurus Protein: HIST1H2AG | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-701034.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | HIST1H2AG | ||||||||
| Protein Name | Histone H2A type 1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000033278 | ||||||||
| InnateDB Gene | IDBG-648276 (HIST1H2AG) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||||||||
| Subcellular Localization | Nucleus. Chromosome. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR002119
Histone H2A IPR003958 Transcription factor CBF/NF-Y/archaeal histone IPR007125 Histone core IPR009072 Histone-fold |
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| PFAM |
PF00808
PF00125 |
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| PRINTS |
PR00620
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| PIRSF | |||||||||
| SMART |
SM00414
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P0C0S9 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 783767 | ||||||||
| UniGene | Bt.88544 | ||||||||
| RefSeq | NP_001092190 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC142109 | ||||||||
| GenPept | AAI42110 | ||||||||