InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gm10221

Summary

InnateDB Protein

IDBP-725109.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gm10221

Protein Name

Synonyms

4933437C06Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000136375

InnateDB Gene

IDBG-215260 (Gm10221)

Protein Structure

UniProt Annotation

Function

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

Subcellular Localization

Mitochondrion. Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015078	hydrogen ion transmembrane transporter activity

Biological Process

GO:0015986

ATP synthesis coupled proton transport

Cellular Component

GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005753	mitochondrial proton-transporting ATP synthase complex

Protein Structure and Domains

PDB ID

MGI:3708709

InterPro

IPR006808 ATPase, F0 complex, subunit G, mitochondrial
IPR016702 Mitochondrial ATP synthase subunit g, animal

PFAM

PF04718

PRINTS

PIRSF

PIRSF017835

SMART

TIGRFAMs