InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rims1

Summary

InnateDB Gene

IDBG-137370.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rims1

Gene Name

regulating synaptic membrane exocytosis 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000041670

Encoded Proteins

IDBP-137372

regulating synaptic membrane exocytosis 1

IDBP-137374

regulating synaptic membrane exocytosis 1

IDBP-137376

regulating synaptic membrane exocytosis 1

IDBP-137378

regulating synaptic membrane exocytosis 1

IDBP-137380

regulating synaptic membrane exocytosis 1

IDBP-249954

regulating synaptic membrane exocytosis 1

IDBP-622821

regulating synaptic membrane exocytosis 1

IDBP-789360

regulating synaptic membrane exocytosis 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079841:
The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:22286251-22805724

Strand

Reverse strand

Band

Transcripts

ENSMUST00000097811	ENSMUSP00000095420
ENSMUST00000097810	ENSMUSP00000095419
ENSMUST00000097809	ENSMUSP00000095418
ENSMUST00000097808	ENSMUSP00000095417
ENSMUST00000081544	ENSMUSP00000080259
ENSMUST00000115273	ENSMUSP00000110928
ENSMUST00000164877	ENSMUSP00000131808
ENSMUST00000185942	ENSMUSP00000140963

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017137	Rab GTPase binding
GO:0044325	ion channel binding
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006461	protein complex assembly
GO:0006886	intracellular protein transport
GO:0042391	regulation of membrane potential
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter