Version 5.4
Mus musculus Gene: Myzap
Summary
InnateDB Gene IDBG-182965.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myzap
Gene Name myocardial zonula adherens protein
Synonyms AA407270; AV006038; Gcom1; Gm640; Grinl1a7; Myozap
Species Mus musculus
Ensembl Gene ENSMUSG00000041361
Encoded Proteins
IDBP-182967
GRINL1A complex locus
IDBP-623518
GRINL1A complex locus
IDBP-623521
GRINL1A complex locus
IDBP-623522
GRINL1A complex locus
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000263155:
This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternate splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstreamstream gene POLR2M (polymerase (RNA) II (DNA directed) polypeptide M). [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:71504347-71592360
Strand Reverse strand
Band D
Transcripts
ENSMUST00000093823 ENSMUSP00000091342
ENSMUST00000163708
ENSMUST00000169573 ENSMUSP00000127028
ENSMUST00000171977 ENSMUSP00000131906
ENSMUST00000166112 ENSMUSP00000131643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0030018 Z disc
GO:0030054 cell junction
GO:0030864 cortical actin cytoskeleton
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031674 I band
Orthologs
Species
Bos taurus
Homo sapiens
Gene ID
Gene Order
ENSBTAG00000002194
Not yet available
ENSG00000263155
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27585
RefSeq NM_001033208
OMIM
CCDS CCDS23327
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca