Version 5.4
Homo sapiens Gene: USP19
Summary
InnateDB Gene IDBG-34363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP19
Gene Name ubiquitin specific peptidase 19
Synonyms ZMYND9
Species Homo sapiens
Ensembl Gene ENSG00000172046
Encoded Proteins
IDBP-34365
ubiquitin specific peptidase 19
IDBP-231870
ubiquitin specific peptidase 19
IDBP-231872
ubiquitin specific peptidase 19
IDBP-231874
ubiquitin specific peptidase 19
IDBP-231876
ubiquitin specific peptidase 19
IDBP-377014
ubiquitin specific peptidase 19
IDBP-377032
ubiquitin specific peptidase 19
IDBP-377037
ubiquitin specific peptidase 19
IDBP-479426
ubiquitin specific peptidase 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:49108046-49120938
Strand Reverse strand
Band p21.31
Transcripts
ENST00000306026 ENSP00000303503
ENST00000398898 ENSP00000381872
ENST00000398896 ENSP00000381870
ENST00000398892 ENSP00000381867
ENST00000398888 ENSP00000381863
ENST00000417901 ENSP00000395260
ENST00000453664 ENSP00000400090
ENST00000434032 ENSP00000401197
ENST00000483667
ENST00000464931
ENST00000479073 ENSP00000428539
ENST00000488993
ENST00000480163
ENST00000491859
ENST00000465902
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 75 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 75 [view]
Protein-Protein 75 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
GO:0036459 ubiquitinyl hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0014732 skeletal muscle atrophy
GO:0016579 protein deubiquitination
GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
GO:0031647 regulation of protein stability
GO:0034976 response to endoplasmic reticulum stress
GO:0048642 negative regulation of skeletal muscle tissue development
GO:0090068 positive regulation of cell cycle process
GO:1900037 regulation of cellular response to hypoxia
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006676
View Gene Order
ENSBTAG00000018921
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.255596 Hs.721972
RefSeq NM_001199160 NM_001199161 NM_001199162 NM_006677 XM_005264823 XM_005264824 XM_005264825 XM_005264826 XM_005264827 XM_005264828 XM_005264829 XM_005264830 XM_005264831 XM_006712946 XM_006712947 XM_006712948 XM_006712950 XM_006712951 XM_006712952 XM_006712953
HUGO
OMIM
CCDS CCDS43090 CCDS56254 CCDS56255 CCDS56256
HPRD 18278
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca