Version 5.4
Bos taurus Gene: CASP4
Summary
InnateDB Gene IDBG-628941.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CASP4
Gene Name Caspase-4 Caspase-4 subunit 1 Caspase-4 subunit 2
Synonyms CASP13
Species Bos taurus
Ensembl Gene ENSBTAG00000020884
Encoded Proteins
IDBP-680346
Caspase-4Caspase-4 subunit 1Caspase-4 subunit 2
IDBP-680356
Caspase-4Caspase-4 subunit 1Caspase-4 subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:3474706-3494168
Strand Forward strand
Band
Transcripts
ENSBTAT00000027820 ENSBTAP00000027820
ENSBTAT00000052006 ENSBTAP00000052549
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0035234 ectopic germ cell programmed cell death
GO:0042981 regulation of apoptotic process
GO:0050718 positive regulation of interleukin-1 beta secretion
GO:0050727 regulation of inflammatory response
GO:0070269 pyroptosis
GO:0097194 execution phase of apoptosis
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0072557 IPAF inflammasome complex
GO:0072559 NLRP3 inflammasome complex
GO:0097169 AIM2 inflammasome complex
Orthologs
No orthologs found for this gene
Cross-References
SwissProt O75601 Q5E9C1
TrEMBL
UniProt Splice Variant
Entrez Gene 338039
UniGene Bt.16018
RefSeq NM_176638 XM_005215725
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF078533 AF383946 AF383947 BC112708 BT020999
GenPept AAC28380 AAI12709 AAK77964 AAK77965 AAX09016
RNA Seq Atlas 338039

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca