Version 5.4
Bos taurus Gene: PFN1
Summary
InnateDB Gene IDBG-634231.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFN1
Gene Name Profilin-1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004915
Encoded Proteins
IDBP-685997
Profilin-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:27081319-27084643
Strand Forward strand
Band
Transcripts
ENSBTAT00000006465 ENSBTAP00000006465
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0001843 neural tube closure
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_202252
Platelet degranulation pathway
REACT_212636
Signaling by Wnt pathway
REACT_212196
Hemostasis pathway
REACT_209572
Platelet activation, signaling and aggregation pathway
REACT_212308
Response to elevated platelet cytosolic Ca2+ pathway
REACT_214353
Signal Transduction pathway
REACT_203140
Axon guidance pathway
REACT_206800
beta-catenin independent WNT signaling pathway
REACT_207926
PCP/CE pathway pathway
REACT_220844
Developmental Biology pathway
REACT_203878
Signaling by Robo receptor pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.23180 Bt.65256 Bt.87105 Bt.90902
RefSeq NM_001015592
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca