Version 5.4
Bos taurus Gene: TLR9
Summary
InnateDB Gene IDBG-645683.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TLR9
Gene Name toll-like receptor 9 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018198
Encoded Proteins
IDBP-698415
toll-like receptor 9 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:49229610-49233939
Strand Forward strand
Band
Transcripts
ENSBTAT00000024223 ENSBTAP00000024223
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0002237 response to molecule of bacterial origin
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0006955 immune response
GO:0007165 signal transduction
GO:0009615 response to virus
GO:0030277 maintenance of gastrointestinal epithelium
GO:0032715 negative regulation of interleukin-6 production
GO:0032728 positive regulation of interferon-beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032741 positive regulation of interleukin-18 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034162 toll-like receptor 9 signaling pathway
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050707 regulation of cytokine secretion
GO:0050727 regulation of inflammatory response
GO:0050729 positive regulation of inflammatory response
GO:0051607 defense response to virus
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
Cellular Component
GO:0005764 lysosome
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0032009 early phagosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL A5H631 G0ZS48 Q4TU53 Q56GY1
UniProt Splice Variant
Entrez Gene 282602
UniGene Bt.12810
RefSeq NM_183081
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY957630 DAAA02054384 DAAA02054385 DQ058825 EF076723 EF076724 EF076725 EF076727 EF076728 EF076729 EF076731 JF330169 JF330170
GenPept AAX56987 AAY58241 ABN71650 ABN71651 ABN71652 ABN71654 ABN71655 ABN71656 ABN71658 AEK31166 AEK31167
RNA Seq Atlas 282602

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca