Bos taurus Protein: TLR9
Summary
InnateDB Protein IDBP-698415.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TLR9
Protein Name toll-like receptor 9 precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024223
InnateDB Gene IDBG-645683 (TLR9)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0002237 response to molecule of bacterial origin
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0006955 immune response
GO:0007165 signal transduction
GO:0009615 response to virus
GO:0030277 maintenance of gastrointestinal epithelium
GO:0032715 negative regulation of interleukin-6 production
GO:0032728 positive regulation of interferon-beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032741 positive regulation of interleukin-18 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034162 toll-like receptor 9 signaling pathway
GO:0045087 innate immune response
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050707 regulation of cytokine secretion
GO:0050727 regulation of inflammatory response
GO:0050729 positive regulation of inflammatory response
GO:0051607 defense response to virus
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
Cellular Component
GO:0005764 lysosome
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0032009 early phagosome
Protein Structure and Domains
PDB ID
InterPro IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01582
PF13676
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00255
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q56GY1
UniProt Splice Variant
Entrez Gene 282602
UniGene Bt.12810
RefSeq NP_898904
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY957630 DAAA02054384 DAAA02054385 DQ058825 EF076723 EF076724 EF076725 EF076727 EF076728 EF076729 EF076731 JF330169 JF330170
GenPept AAX56987 AAY58241 ABN71650 ABN71651 ABN71652 ABN71654 ABN71655 ABN71656 ABN71658 AEK31166 AEK31167