Version 5.4
Bos taurus Gene: SPINK1
Summary
InnateDB Gene IDBG-646189.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPINK1
Gene Name Pancreatic secretory trypsin inhibitor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015558
Encoded Proteins
IDBP-698970
Pancreatic secretory trypsin inhibitor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:61042755-61049774
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020673 ENSBTAP00000020673
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0010466 negative regulation of peptidase activity
GO:0010751 negative regulation of nitric oxide mediated signal transduction
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0060046 regulation of acrosome reaction
GO:0090281 negative regulation of calcium ion import
GO:1900004 negative regulation of serine-type endopeptidase activity
GO:2001256 regulation of store-operated calcium entry
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P00996
TrEMBL
UniProt Splice Variant
Entrez Gene 574092
UniGene Bt.9636
RefSeq NM_001025348
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY911325 BC102485
GenPept AAI02486 AAW82093
RNA Seq Atlas 574092

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca