Version 5.4
Bos taurus Gene: ENTPD5
Summary
InnateDB Gene IDBG-646846.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENTPD5
Gene Name Ectonucleoside triphosphate diphosphohydrolase 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020334
Encoded Proteins
IDBP-699685
Ectonucleoside triphosphate diphosphohydrolase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187097:
The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:85743347-85759039
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027098 ENSBTAP00000027098
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004382 guanosine-diphosphatase activity
GO:0016787 hydrolase activity
GO:0017110 nucleoside-diphosphatase activity
GO:0045134 uridine-diphosphatase activity
Biological Process
GO:0006486 protein glycosylation
GO:0006487 protein N-linked glycosylation
GO:0008283 cell proliferation
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling
GO:0016049 cell growth
GO:0045821 positive regulation of glycolytic process
GO:0046034 ATP metabolic process
GO:0051084 'de novo' posttranslational protein folding
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000187097
View Gene Order
ENSMUSG00000021236
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt E1BPW0
TrEMBL G5E5P3
UniProt Splice Variant
Entrez Gene 533096
UniGene Bt.103949 Bt.14106
RefSeq NM_001192752 XM_005211989 XM_005211990 XM_005211991 XM_005211992
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03056279 DAAA02029604
GenPept
RNA Seq Atlas 533096

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca