Version 5.4
Homo sapiens Gene: ABT1
Summary
InnateDB Gene IDBG-69653.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABT1
Gene Name activator of basal transcription 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146109
Encoded Proteins
IDBP-69655
activator of basal transcription 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:26596952-26600744
Strand Forward strand
Band p22.2
Transcripts
ENST00000274849 ENSP00000274849
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0021522 spinal cord motor neuron differentiation
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036376
View Gene Order
ENSBTAG00000010784
Not yet available
Cross-References
SwissProt Q9ULW3
TrEMBL A0A024R029
UniProt Splice Variant
Entrez Gene 29777
UniGene Hs.254406
RefSeq NM_013375
HUGO HGNC:17369
OMIM
CCDS CCDS4616
HPRD
IMGT
EMBL AB027258 AL513548 BC048812 BC066313 CH471087
GenPept AAH48812 AAH66313 BAA86886 CAC40824 EAW55591 EAW55593
RNA Seq Atlas 29777

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca