InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABT1

Summary

InnateDB Protein

IDBP-69655.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABT1

Protein Name

activator of basal transcription 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000274849

InnateDB Gene

IDBG-69653 (ABT1)

Protein Structure

UniProt Annotation

Function

Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0021522	spinal cord motor neuron differentiation