InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slitrk6

Summary

InnateDB Protein

IDBP-185911.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slitrk6

Protein Name

SLIT and NTRK-like family, member 6

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000077492

InnateDB Gene

IDBG-185909 (Slitrk6)

Protein Structure

UniProt Annotation

Function

Regulator of neurite outgrowth required for normal hearing and vision. {ECO:0000269PubMed:14550773, ECO:0000269PubMed:23543054}.

Subcellular Localization

Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

In the embryo, expressed in otic cyst, lateral trunk epidermis and underlying mesodermal tissue, limb bud, maxillary process, cochlea, retina, tongue, tooth primordium, central nervous system, and primordia of visceral organs including lung, gastrointestinal tract and pancreas. In the central nervous system, expressed primarily in dorsal thalamus, cerebellum and medulla. {ECO:0000269PubMed:14643680}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0001964	startle response
GO:0002088	lens development in camera-type eye
GO:0002093	auditory receptor cell morphogenesis
GO:0007409	axonogenesis
GO:0007416	synapse assembly
GO:0007601	visual perception
GO:0007605	sensory perception of sound
GO:0008344	adult locomotory behavior
GO:0021562	vestibulocochlear nerve development
GO:0031223	auditory behavior
GO:0035264	multicellular organism growth
GO:0042472	inner ear morphogenesis
GO:0043010	camera-type eye development
GO:0048812	neuron projection morphogenesis
GO:0060005	vestibular reflex
GO:0060007	linear vestibuloocular reflex
GO:0060384	innervation
GO:0090102	cochlea development