Version 5.4
Homo sapiens Protein: ALDH1A2
Summary
InnateDB Protein IDBP-591391.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH1A2
Protein Name aldehyde dehydrogenase 1 family, member A2
Synonyms RALDH(II); RALDH2; RALDH2-T;
Species Homo sapiens
Ensembl Protein ENSP00000453408
InnateDB Gene IDBG-13982 (ALDH1A2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001758 retinal dehydrogenase activity
GO:0004028 3-chloroallyl aldehyde dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016918 retinal binding
Biological Process
GO:0006776 vitamin A metabolic process
GO:0008152 metabolic process
GO:0008285 negative regulation of cell proliferation
GO:0021915 neural tube development
GO:0034097 response to cytokine
GO:0042572 retinol metabolic process
GO:0042573 retinoic acid metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF00171
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94788
PhosphoSite PhosphoSite-O94788
TrEMBL Q9UED3
UniProt Splice Variant
Entrez Gene 8854
UniGene Hs.716113
RefSeq NP_733798
HUGO HGNC:15472
OMIM 603687
CCDS CCDS45266
HPRD 04733
IMGT
EMBL AB015226 AB015227 AB015228 AB015229 AC012653 AC018904 AC025431 AC066616 AC084781 AK128709 AK303057 AL110299 BC030589 DQ322171
GenPept AAH30589 ABC40749 BAA34785 BAA34786 BAA34787 BAA34788 BAG54714 BAG64174 CAB53740

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca