InnateDB Protein
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IDBP-8226.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SYNGR1
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Protein Name
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synaptogyrin 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000332287
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InnateDB Gene
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IDBG-8224 (SYNGR1)
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Protein Structure
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Function |
Involved in the regulation of short-term and long-term synaptic plasticity. {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000269PubMed:17081065}; Multi-pass membrane protein {ECO:0000269PubMed:17081065}. Melanosome {ECO:0000269PubMed:17081065}. Cell junction, synapse {ECO:0000269PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
GO:0006605
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protein targeting
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GO:0048169
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regulation of long-term neuronal synaptic plasticity
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GO:0048172
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regulation of short-term neuronal synaptic plasticity
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Cellular Component |
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PDB ID |
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InterPro |
IPR008253
Marvel domain
IPR016579
Synaptogyrin
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PFAM |
PF01284
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PRINTS |
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PIRSF |
PIRSF011282
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O43759
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PhosphoSite |
PhosphoSite-O43759
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9145
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UniGene |
Hs.216226
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RefSeq |
NP_004702
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HUGO |
HGNC:11498
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OMIM |
603925
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CCDS |
CCDS13989
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HPRD |
06800
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IMGT |
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EMBL |
AJ002303
AJ002304
AJ002305
AK289507
AL022326
BC000731
BT007135
CR456590
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GenPept |
AAH00731
AAP35799
BAF82196
CAA05320
CAA05321
CAA05322
CAA18452
CAG30476
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