Version 5.4
Homo sapiens Gene: SYNGR1
Summary
InnateDB Gene IDBG-8224.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNGR1
Gene Name synaptogyrin 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100321
Encoded Proteins
IDBP-8226
synaptogyrin 1
IDBP-8228
synaptogyrin 1
IDBP-8230
synaptogyrin 1
IDBP-8232
synaptogyrin 1
IDBP-293436
synaptogyrin 1
IDBP-377228
synaptogyrin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:39349925-39385588
Strand Forward strand
Band q13.1
Transcripts
ENST00000328933 ENSP00000332287
ENST00000318801 ENSP00000318845
ENST00000216155 ENSP00000216155
ENST00000381535 ENSP00000370946
ENST00000406293 ENSP00000385447
ENST00000415332 ENSP00000412442
ENST00000489206
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006605 protein targeting
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048172 regulation of short-term neuronal synaptic plasticity
Cellular Component
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0042470 melanosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022415
View Gene Order
ENSBTAG00000005765
Not yet available
Cross-References
SwissProt O43759
TrEMBL A2A283 B5MCD7 F8WCE4
UniProt Splice Variant
Entrez Gene 9145
UniGene Hs.216226
RefSeq NM_004711 NM_145731 NM_145738
HUGO HGNC:11498
OMIM 603925
CCDS CCDS13989 CCDS13990 CCDS13991
HPRD
IMGT
EMBL AJ002303 AJ002304 AJ002305 AK289507 AK295863 AL022326 BC000731 BT007135 CR456590
GenPept AAH00731 AAP35799 BAF82196 BAH12206 CAA05320 CAA05321 CAA05322 CAA18452 CAG30476
RNA Seq Atlas 9145

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca