Version 5.4
Homo sapiens Protein: SYNGR1
Summary
InnateDB Protein IDBP-8232.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNGR1
Protein Name synaptogyrin 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000370946
InnateDB Gene IDBG-8224 (SYNGR1)
Protein Structure
UniProt Annotation
Function Involved in the regulation of short-term and long-term synaptic plasticity. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000269PubMed:17081065}; Multi-pass membrane protein {ECO:0000269PubMed:17081065}. Melanosome {ECO:0000269PubMed:17081065}. Cell junction, synapse {ECO:0000269PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048172 regulation of short-term neuronal synaptic plasticity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0042470 melanosome
Protein Structure and Domains
PDB ID
InterPro IPR008253 Marvel domain
PFAM PF01284
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43759
PhosphoSite PhosphoSite-O43759
TrEMBL
UniProt Splice Variant
Entrez Gene 9145
UniGene Hs.216226
RefSeq NP_663791
HUGO HGNC:11498
OMIM 603925
CCDS CCDS13991
HPRD 06800
IMGT
EMBL AJ002303 AJ002304 AJ002305 AK289507 AL022326 BC000731 BT007135 CR456590
GenPept AAH00731 AAP35799 BAF82196 CAA05320 CAA05321 CAA05322 CAA18452 CAG30476

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca