Version 5.4
Homo sapiens Gene: DENND5B
Summary
InnateDB Gene IDBG-26012.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DENND5B
Gene Name DENN/MADD domain containing 5B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170456
Encoded Proteins
IDBP-26016
DENN/MADD domain containing 5B
IDBP-26018
DENN/MADD domain containing 5B
IDBP-589051
DENN/MADD domain containing 5B
IDBP-589808
DENN/MADD domain containing 5B
IDBP-592125
DENN/MADD domain containing 5B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:31382223-31591097
Strand Reverse strand
Band p11.21
Transcripts
ENST00000354285 ENSP00000346238
ENST00000389082 ENSP00000373734
ENST00000536562 ENSP00000444889
ENST00000537061
ENST00000546299 ENSP00000442938
ENST00000545147
ENST00000544698 ENSP00000445113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030313
View Gene Order
ENSBTAG00000020315
Not yet available
Cross-References
SwissProt Q6ZUT9
TrEMBL
UniProt Splice Variant
Entrez Gene 160518
UniGene Hs.118166 Hs.630486 Hs.630714
RefSeq NM_144973 XM_006719040
HUGO HGNC:28338
OMIM
CCDS CCDS44857
HPRD 11321
IMGT
EMBL AB209341 AC022080 AC068792 AK095598 AK125323 BC020855 BC068580 BX537924 CH471116 CR749639
GenPept AAH20855 AAH68580 BAC04583 BAC86129 BAD92578 CAD97905 CAH18433 EAW88553
RNA Seq Atlas 160518

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca