Version 5.4
Interaction: SP1 :: MYC XML
Summary
InnateDB Group ID 348857
Short name SP1 :: MYC
Full name SP1 interacts with MYC
Interaction type physical association
Participants
Participant 1
Molecule: IDBG-36616
Molecule type: protein
Species: Homo sapiens
HUGO: SP1
Full name: Sp1 transcription factor
Direction: input
Biological role: unspecified role
Participant 2
Molecule: IDBG-35442
Molecule type: protein
Species: Homo sapiens
HUGO: MYC
Full name: v-myc myelocytomatosis viral oncogene homolog (avian)
Direction: input
Biological role: unspecified role
Evidence Reference 1
InnateDB ID IDB-252236.1
Last Modified 2012-02-14
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-519986
PMID 17418410
Interaction detection method affinity chromatography technology
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) MYC predetermined participant bait NP_002458
2) SP1 predetermined participant prey 6667
Evidence Reference 2
InnateDB ID IDB-252441.1
Last Modified 2012-02-14
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-518135
PMID 18003922
Interaction detection method affinity chromatography technology
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) MYC predetermined participant bait NP_002458
2) SP1 predetermined participant prey 6667
Evidence Reference 3
InnateDB ID IDB-256129.1
Last Modified 2012-02-14
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-519990
PMID 17418410
Interaction detection method affinity chromatography technology
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 predetermined participant bait 6667
2) MYC predetermined participant prey NP_002458
Evidence Reference 4
InnateDB ID IDB-300293.1
Last Modified 2012-02-14
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-280203
PMID 11274368
Interaction detection method affinity chromatography technology
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 predetermined participant bait 6667
2) MYC predetermined participant prey NP_002458
Evidence Reference 5
InnateDB ID IDB-1077741.1
Last Modified 2013-07-09
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIOGRID
Source database ID BIOGRID-858124
PMID 15780936
Interaction detection method affinity chromatography technology
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 predetermined participant bait 6667
2) MYC predetermined participant prey NP_002458
Evidence Reference 6
InnateDB ID IDB-2063537.1
Last Modified 2018-01-20
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB
Source database ID IDB-2063537
PMID 15780936
Interaction detection method anti bait coimmunoprecipitation
Host system invitro
Host organism Homo sapiens
Cell status cell line
Cell line HCT116
Cell type
Tissue type
Comment Figure 5B.
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 identification by antibody bait
2) MYC western blot prey
Evidence Reference 7
InnateDB ID IDB-2063537.1
Last Modified 2018-01-20
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB ALLERGY
Source database ID AAP-2063537
PMID 15780936
Interaction detection method anti bait coimmunoprecipitation
Host system invitro
Host organism Homo sapiens
Cell status cell line
Cell line HCT116
Cell type
Tissue type
Comment Figure 5B.
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 identification by antibody bait
2) MYC western blot prey
Evidence Reference 8
InnateDB ID IDB-2063540.1
Last Modified 2018-01-20
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB
Source database ID IDB-2063540
PMID 15780936
Interaction detection method anti bait coimmunoprecipitation
Host system invitro
Host organism Homo sapiens
Cell status cell line
Cell line HCT116
Cell type
Tissue type
Comment Figure 5C. 35S methionine-labelled MYC co-immunoprecipitated with anti-SP1.
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 identification by antibody bait
2) MYC autoradiography prey
Evidence Reference 9
InnateDB ID IDB-2063540.1
Last Modified 2018-01-20
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB ALLERGY
Source database ID AAP-2063540
PMID 15780936
Interaction detection method anti bait coimmunoprecipitation
Host system invitro
Host organism Homo sapiens
Cell status cell line
Cell line HCT116
Cell type
Tissue type
Comment Figure 5C. 35S methionine-labelled MYC co-immunoprecipitated with anti-SP1.
Participants
Participant Identification Method Experimental Role Participant Accession
1) SP1 identification by antibody bait
2) MYC autoradiography prey

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca